Details for gene set G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.15309012
Normalized Enrichment Score (NES)	-3.156868
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GPR15	50	2.781	0.0003	No
2	RHO	62	2.642	0.0028	No
3	OPRD1	66	2.581	0.0057	No
4	GABRA1	87	2.226	0.0076	No
5	GCGR	93	2.179	0.0104	No
6	CCL25	115	2.021	0.0123	No
7	APOA1	140	1.901	0.0141	No
8	SST	144	1.881	0.0170	No
9	GRM5	156	1.783	0.0194	No
10	F2RL3	164	1.710	0.0221	No
11	SSTR4	172	1.642	0.0248	No
12	GPR32	212	1.488	0.0257	No
13	HTR2A	241	1.367	0.0272	No
14	CCKBR	274	1.281	0.0286	No
15	GPR25	361	1.081	0.0269	No
16	TAC3	376	1.054	0.0292	No
17	NMBR	392	1.026	0.0314	No
18	MTNR1A	398	1.015	0.0342	No
19	MTNR1B	414	1.008	0.0365	No
20	GRM1	470	0.943	0.0365	No
21	MS4A2	478	0.938	0.0392	No
22	GALR1	513	0.878	0.0404	No
23	CHRM3	535	0.848	0.0423	No
24	SSTR3	579	0.791	0.0430	No
25	GCG	610	0.756	0.0444	No
26	NPY5R	641	0.734	0.0459	No
27	HTR2B	649	0.728	0.0485	No
28	RASD1	659	0.717	0.0511	No
29	NPY1R	670	0.710	0.0536	No
30	GLRA1	717	0.667	0.0542	No
31	GPR3	741	0.644	0.0560	No
32	GRM8	778	0.623	0.0570	No
33	GABRA2	825	0.609	0.0576	No
34	GABRA4	858	0.589	0.0589	No
35	LPAR4	880	0.574	0.0608	No
36	GLRA2	898	0.570	0.0629	No
37	ADCYAP1	901	0.569	0.0659	No
38	GALR3	910	0.567	0.0685	No
39	ADRB3	923	0.559	0.0709	No
40	DRD1	924	0.558	0.0740	No
41	XPR1	962	0.541	0.0750	No
42	MLN	971	0.537	0.0776	No
43	CCL3	1030	0.503	0.0775	No
44	CCL23	1042	0.499	0.0800	No
45	CALCR	1066	0.494	0.0818	No
46	OR10J1	1070	0.494	0.0847	No
47	HCAR3	1071	0.493	0.0877	No
48	AKAP12	1095	0.484	0.0895	No
49	CCL17	1203	0.437	0.0867	No
50	PLCE1	1235	0.428	0.0881	No
51	F2RL1	1257	0.421	0.0900	No
52	QRFPR	1258	0.421	0.0931	No
53	GPR75	1274	0.416	0.0953	No
54	HTR1D	1309	0.401	0.0965	No
55	RGS4	1311	0.401	0.0995	No
56	GPR45	1385	0.376	0.0986	No
57	HTR1E	1492	0.349	0.0959	No
58	HTR7	1654	0.318	0.0901	No
59	GLP1R	1656	0.318	0.0931	No
60	GABRR1	1737	0.304	0.0918	No
61	PTHLH	1769	0.298	0.0932	No
62	GPR34	1911	0.273	0.0885	No
63	RGS20	1987	0.263	0.0875	No
64	CCR3	2026	0.259	0.0885	No
65	GNG4	2042	0.257	0.0907	No
66	GHRHR	2145	0.246	0.0882	No
67	S1PR1	2153	0.245	0.0909	No
68	GPR12	2186	0.241	0.0922	No
69	LGR5	2196	0.239	0.0948	No
70	OPN1MW	2210	0.237	0.0971	No
71	MAS1	2269	0.231	0.0970	No
72	GABRB2	2287	0.229	0.0991	No
73	RGS5	2407	0.217	0.0957	No
74	FSHR	2477	0.211	0.0950	No
75	PRLHR	2503	0.210	0.0967	No
76	S1PR2	2591	0.203	0.0950	No
77	GPR183	2599	0.202	0.0976	No
78	CHRM2	2981	0.174	0.0799	No
79	CAP2	3028	0.171	0.0804	No
80	NF1	3060	0.169	0.0818	No
81	GPR22	3117	0.165	0.0818	No
82	HOMER1	3260	0.157	0.0771	No
83	GABRA3	3303	0.155	0.0779	No
84	HCRTR1	3447	0.148	0.0731	No
85	P2RY4	3560	0.142	0.0700	No
86	ADCY7	3647	0.138	0.0684	No
87	CXCR4	3670	0.137	0.0703	No
88	GIT2	3735	0.134	0.0698	No
89	RIC8B	3790	0.131	0.0699	No
90	HTR4	3825	0.129	0.0711	No
91	GNB3	3852	0.128	0.0728	No
92	GNAS	3869	0.128	0.0749	No
93	GABRG2	3891	0.127	0.0769	No
94	PIK3CG	3956	0.124	0.0764	No
95	ANG	4182	0.115	0.0672	No
96	P2RY1	4196	0.115	0.0695	No
97	FRS2	4219	0.114	0.0714	No
98	PREX2	4296	0.112	0.0703	No
99	PRKD3	4499	0.105	0.0623	No
100	CCR10	4516	0.104	0.0645	No
101	ABCA1	4659	0.099	0.0598	No
102	CNR2	4697	0.098	0.0608	No
103	CCR2	4737	0.096	0.0618	No
104	PRKACB	4816	0.094	0.0606	No
105	PIK3CB	4965	0.090	0.0555	No
106	CX3CR1	5260	0.082	0.0425	No
107	ENPP2	5374	0.079	0.0394	No
108	AKT1	5405	0.078	0.0408	No
109	GPR68	5438	0.077	0.0421	No
110	RGS3	5455	0.077	0.0443	No
111	AGRN	5517	0.075	0.0440	No
112	HRH2	5735	0.069	0.0353	No
113	C5	5772	0.068	0.0363	No
114	GPR4	5797	0.067	0.0381	No
115	AVPR1A	5904	0.064	0.0354	No
116	LANCL1	5969	0.063	0.0349	No
117	RAMP1	6024	0.062	0.0350	No
118	EDNRA	6041	0.061	0.0372	No
119	WASF2	6204	0.058	0.0314	No
120	GLRB	6295	0.055	0.0296	No
121	UCN	6449	0.051	0.0243	No
122	APOC3	6521	0.050	0.0234	No
123	GPR1	6638	0.048	0.0202	No
124	CCRL2	6864	0.043	0.0109	No
125	GRK5	6905	0.042	0.0118	No
126	RGS9	6906	0.042	0.0149	No
127	GRPR	6947	0.041	0.0157	No
128	GNAI3	6993	0.040	0.0163	No
129	CALM3	7021	0.039	0.0179	No
130	GABBR1	7283	0.034	0.0067	No
131	HOMER2	7375	0.031	0.0048	No
132	GABRE	7435	0.030	0.0046	No
133	ADORA2B	7487	0.029	0.0049	No
134	P2RY2	7524	0.028	0.0060	No
135	GNG7	7661	0.026	0.0016	No
136	BCAR1	7827	0.023	-0.0043	No
137	HTR1B	7869	0.022	-0.0035	No
138	GNB1	7899	0.021	-0.0020	No
139	DRD2	7972	0.020	-0.0029	No
140	GRK4	8128	0.017	-0.0083	No
141	GNAQ	8139	0.017	-0.0058	No
142	DRD4	8250	0.014	-0.0088	No
143	EDNRB	8261	0.014	-0.0063	No
144	OPN3	8278	0.014	-0.0041	No
145	ARHGEF11	9049	-0.002	-0.0431	No
146	SCTR	9051	-0.002	-0.0401	No
147	C3AR1	9063	-0.002	-0.0376	No
148	GNA12	9087	-0.003	-0.0358	No
149	PPAP2A	9181	-0.005	-0.0378	No
150	RGS1	9288	-0.007	-0.0406	No
151	GNAZ	9374	-0.008	-0.0422	No
152	GPR17	9423	-0.009	-0.0417	No
153	GIT1	9628	-0.014	-0.0498	No
154	GRP	9653	-0.014	-0.0481	No
155	PDC	10015	-0.021	-0.0647	No
156	PICK1	10017	-0.021	-0.0617	No
157	PTGIR	10040	-0.021	-0.0599	No
158	GPR176	10154	-0.023	-0.0630	No
159	C5AR1	10286	-0.026	-0.0671	No
160	CXCL12	10425	-0.028	-0.0716	No
161	GNAI2	10460	-0.029	-0.0704	No
162	MLNR	10637	-0.033	-0.0769	No
163	HRH1	10734	-0.035	-0.0791	No
164	GRM2	10857	-0.038	-0.0827	No
165	CCR1	10867	-0.038	-0.0801	No
166	VIPR1	10969	-0.041	-0.0826	No
167	GNB2	11079	-0.044	-0.0855	No
168	MC1R	11228	-0.047	-0.0905	No
169	CAP1	11285	-0.048	-0.0905	No
170	TBL3	11349	-0.050	-0.0909	No
171	RGS11	11483	-0.053	-0.0951	No
172	RGS12	11594	-0.055	-0.0981	No
173	GPR21	11630	-0.056	-0.0969	No
174	GAP43	11679	-0.058	-0.0965	No
175	GPRC5C	11680	-0.058	-0.0934	No
176	EGFR	11807	-0.060	-0.0973	No
177	VIP	11935	-0.064	-0.1011	No
178	BUD31	12052	-0.066	-0.1044	No
179	ADORA3	12298	-0.072	-0.1147	No
180	AVPR2	12302	-0.072	-0.1119	No
181	XCR1	12415	-0.075	-0.1149	No
182	RGS2	12476	-0.077	-0.1151	No
183	TACR2	12504	-0.078	-0.1136	No
184	ADRA1B	12594	-0.080	-0.1154	No
185	TBXA2R	12664	-0.082	-0.1161	No
186	GRK6	12743	-0.085	-0.1173	No
187	LTB4R2	12821	-0.087	-0.1184	No
188	GPR19	12848	-0.088	-0.1168	No
189	PARD3	13008	-0.092	-0.1224	No
190	SSTR1	13028	-0.093	-0.1204	No
191	GPR65	13033	-0.093	-0.1176	No
192	ADRB2	13083	-0.094	-0.1172	No
193	HOMER3	13276	-0.101	-0.1246	No
194	CCKAR	13360	-0.104	-0.1261	No
195	PTGER4	13389	-0.105	-0.1246	No
196	GPSM2	13583	-0.111	-0.1320	No
197	GIPR	13604	-0.112	-0.1301	No
198	NMUR1	13663	-0.114	-0.1302	No
199	CXCR6	13714	-0.116	-0.1299	No
200	GPR123	13831	-0.121	-0.1331	No
201	P2RY6	13923	-0.125	-0.1350	No
202	RAPGEF4	13966	-0.126	-0.1343	No
203	CALCRL	13989	-0.128	-0.1324	No
204	GRM3	14032	-0.130	-0.1317	No
205	CRHR2	14080	-0.132	-0.1312	No
206	TACR3	14337	-0.146	-0.1421	No
207	GPR20	14352	-0.147	-0.1398	No
208	CORT	14363	-0.147	-0.1373	No
209	PTPN6	14496	-0.153	-0.1415	No
210	LPAR2	14657	-0.161	-0.1471	No
211	ACR	14762	-0.168	-0.1498	No
212	CCR5	14824	-0.173	-0.1500	Yes
213	PTGFR	14838	-0.174	-0.1477	Yes
214	LPAR3	14884	-0.177	-0.1471	Yes
215	OPRL1	14942	-0.181	-0.1471	Yes
216	SPHK1	15038	-0.188	-0.1493	Yes
217	CXCL1	15044	-0.189	-0.1465	Yes
218	AGRP	15160	-0.197	-0.1497	Yes
219	AGTR1	15193	-0.200	-0.1484	Yes
220	RAPGEFL1	15198	-0.201	-0.1456	Yes
221	ADRA2C	15245	-0.204	-0.1450	Yes
222	CHRM1	15266	-0.206	-0.1431	Yes
223	RGS19	15271	-0.206	-0.1402	Yes
224	PTH1R	15314	-0.210	-0.1394	Yes
225	CHRM5	15320	-0.211	-0.1367	Yes
226	GRM6	15452	-0.222	-0.1408	Yes
227	S1PR3	15492	-0.227	-0.1398	Yes
228	P2RY11	15504	-0.228	-0.1374	Yes
229	LTB4R	15563	-0.233	-0.1375	Yes
230	GNA15	15687	-0.247	-0.1412	Yes
231	HTR1F	15742	-0.255	-0.1410	Yes
232	NPFFR2	15784	-0.261	-0.1402	Yes
233	LHCGR	15805	-0.264	-0.1383	Yes
234	GNRHR	15835	-0.268	-0.1368	Yes
235	HCRTR2	15851	-0.269	-0.1345	Yes
236	ADRB1	15883	-0.273	-0.1332	Yes
237	ADRA1A	15890	-0.274	-0.1305	Yes
238	APLNR	15965	-0.283	-0.1314	Yes
239	ADRA2B	15993	-0.287	-0.1299	Yes
240	PTAFR	15996	-0.287	-0.1269	Yes
241	PLCB2	16031	-0.291	-0.1257	Yes
242	C3	16057	-0.294	-0.1240	Yes
243	CDK5R1	16109	-0.301	-0.1237	Yes
244	PTGER2	16220	-0.322	-0.1267	Yes
245	QRFP	16224	-0.323	-0.1238	Yes
246	TSHR	16242	-0.326	-0.1217	Yes
247	FFAR1	16288	-0.332	-0.1211	Yes
248	CD3E	16300	-0.334	-0.1186	Yes
249	S1PR4	16446	-0.365	-0.1235	Yes
250	MC5R	16498	-0.377	-0.1232	Yes
251	GALR2	16500	-0.377	-0.1202	Yes
252	GPR35	16507	-0.378	-0.1175	Yes
253	MC4R	16517	-0.380	-0.1149	Yes
254	FPR2	16549	-0.387	-0.1135	Yes
255	GPR52	16554	-0.389	-0.1107	Yes
256	CCL2	16640	-0.407	-0.1123	Yes
257	RRH	16653	-0.411	-0.1099	Yes
258	GLP2R	16676	-0.419	-0.1080	Yes
259	RGS14	16717	-0.431	-0.1072	Yes
260	PTGER3	16718	-0.431	-0.1041	Yes
261	MCHR1	16745	-0.436	-0.1025	Yes
262	OXGR1	16776	-0.446	-0.1010	Yes
263	OPRM1	16799	-0.453	-0.0992	Yes
264	ADRA1D	16824	-0.461	-0.0974	Yes
265	NTSR1	16833	-0.464	-0.0948	Yes
266	NMUR2	16900	-0.480	-0.0954	Yes
267	GPR55	16960	-0.493	-0.0955	Yes
268	GHRL	17024	-0.509	-0.0959	Yes
269	APOE	17052	-0.519	-0.0943	Yes
270	SSTR2	17118	-0.542	-0.0948	Yes
271	AZU1	17141	-0.551	-0.0930	Yes
272	HRH3	17186	-0.572	-0.0923	Yes
273	ADRA2A	17190	-0.575	-0.0894	Yes
274	CALY	17239	-0.598	-0.0890	Yes
275	NPBWR1	17252	-0.603	-0.0866	Yes
276	GRK1	17282	-0.619	-0.0851	Yes
277	PTGER1	17292	-0.625	-0.0825	Yes
278	SSTR5	17301	-0.629	-0.0799	Yes
279	CNR1	17364	-0.661	-0.0802	Yes
280	FFAR2	17445	-0.700	-0.0816	Yes
281	CHRM4	17448	-0.703	-0.0786	Yes
282	GABBR2	17458	-0.711	-0.0760	Yes
283	IL8	17463	-0.715	-0.0732	Yes
284	TSHB	17474	-0.720	-0.0707	Yes
285	FPR1	17496	-0.733	-0.0688	Yes
286	HTR6	17531	-0.751	-0.0676	Yes
287	NPY2R	17535	-0.755	-0.0647	Yes
288	CALCA	17537	-0.756	-0.0617	Yes
289	EDN2	17572	-0.781	-0.0605	Yes
290	CXCR2	17578	-0.784	-0.0577	Yes
291	GRM4	17584	-0.793	-0.0549	Yes
292	GPR37	17610	-0.815	-0.0532	Yes
293	DRD5	17619	-0.823	-0.0506	Yes
294	OPRK1	17632	-0.832	-0.0482	Yes
295	CRHR1	17641	-0.840	-0.0456	Yes
296	DRD3	17661	-0.852	-0.0436	Yes
297	TRHR	17681	-0.870	-0.0415	Yes
298	TACR1	17708	-0.891	-0.0399	Yes
299	ECEL1	17880	-1.019	-0.0462	Yes
300	MC3R	17929	-1.072	-0.0457	Yes
301	TAAR6	17954	-1.090	-0.0440	Yes
302	RGS16	17973	-1.101	-0.0419	Yes
303	BDKRB2	17981	-1.110	-0.0392	Yes
304	RGR	17985	-1.115	-0.0364	Yes
305	FFAR3	18009	-1.141	-0.0346	Yes
306	CCR8	18056	-1.191	-0.0340	Yes
307	NPY	18089	-1.220	-0.0327	Yes
308	GPR42	18123	-1.276	-0.0314	Yes
309	HTR1A	18127	-1.294	-0.0285	Yes
310	GRM7	18130	-1.297	-0.0256	Yes
311	GHSR	18156	-1.347	-0.0239	Yes
312	OR1D5	18208	-1.443	-0.0236	Yes
313	CCR9	18261	-1.511	-0.0234	Yes
314	PYY	18276	-1.536	-0.0211	Yes
315	RXFP3	18287	-1.555	-0.0186	Yes
316	GPR39	18325	-1.661	-0.0176	Yes
317	DEFB1	18367	-1.831	-0.0168	Yes
318	AVPR1B	18370	-1.854	-0.0138	Yes
319	GHRH	18373	-1.859	-0.0109	Yes
320	TAS2R1	18389	-1.938	-0.0086	Yes
321	CASR	18393	-1.955	-0.0057	Yes
322	CXCL9	18404	-1.987	-0.0032	Yes
323	CXCR5	18405	-1.989	-0.0002	Yes
324	MC2R	18444	-2.148	0.0008	Yes
325	GPR31	18516	-2.916	0.0000	Yes
326	GPR50	18539	-3.606	0.0019	Yes
327	TAAR1	18614	-17.501	0.0009	Yes